Both administrations failed, but this fascist stain on democracy set the politicization in motion. I'm keeping this pinned and will retweet regularly to remind people until after the election.
I see my comment from last night brought out the trolls in big numbers. HIV primarily causes damage to the immune system. COVID causes damage to every system. HIV can be easily managed with ART. There is nothing to manage the damage from COVID. Thanks for attending my TED Talk.
Some context using infection to disease:
HIV to AIDS ~ 12 years (mean)
HPV to cervical cancer ~ up to decades
Spanish Flu to encephalitis lethargica ~ temporal association suggests up to a decade
COVID to chronic diseases ~ weeks
We are just seeing the tip of the icerberg.
Let me put H5N1 in perspective in terms of COVID. H5N1 is what I have been speaking about for years. It would be >100x worse than COVID assuming it maintains the mortality levels we have seen with it historically. In other terms, 1 billion deaths.
"Now in China, the doubling time is like hours."
Goodbye pharmaceuticals, other supply chains, and the global economy. This is the surge I've been warning about.
When I get stunned, it's a bad sign. That's where I'm at right now. This is hospital admissions in the NYC metro area. See the black peak at the end of the red arrow? That was one week ago. This is going to get SO bad SO quickly.
More marine mammals with H5N1. I haven't slept well for over a week, and the last couple of night have been particularly bad. I expect tonight to be worse.
Pay attention to how they are dressed to work with SARS-COV-2, then look at how people are dressed at your local market, your workplace, or your local schools. See the difference?
SARS-COV-2 CELL ENTRY, ACE2 and TMPRSS2
(layman terms - 2nd part)
Certainly, researchers like Stuart
@StuartTurville
are in a speed race with this virus which mutates very quickly but we MUST NOT CONFUSE SPEED with PRECIPITATION.
US.
I'm old enough to remember when the WHO recommended government interventions when positivity was over 5%. We are going to suffer very badly this round.
I have an explanation...
"Never before in the past three years have so many children between the ages of five and fourteen with pneumonia visited their GP in one week as last week. There is as yet no explanation for this large number."
I'm beginning to think that the collapse of complex systems, including civilization, has a very long tail with many warning indicators that go unheeded, and then accelerates at an astonishing pace.
Yes, the pandemic is driving depression. I never fathomed how many people are racists, eugenecists, and charlatans driven by power and greed. I've emptied my life of people who had me fooled about who they really were and it has left me lonely.
1-2
No mention of COVID in this piece. People seem to think that it's an acute respiratory illness and then recover. The fact is that it is an endovascular disease and can precipitate strokes in the future.
Walgreens hid their COVID positivity data in the last couple of weeks. Carnegie Mellon has hidden their Quidel lab data I had been using. What is going on? Fortunately, I found some PCR data to use, but I can't help but go down a conspiracy rabbit hole lately.
I have somewhat avoided the monkeypox topic since I really don't want to deal with the same crowd accusing me of fearmongering again, but we are in deep trouble with what is shaping up to be two concurrent pandemics.
This is the reference lab I use for the antigen positivity rates in my state charts. I've created a graph for this for the entire country. We are in trouble.
More evidence for my Tweet a couple of days ago about France and Germany. Hospitalizations from COVID in Germany are at their highest ever, and this wave is only barely started. The fact that it's a near vertical line should raise eyebrows too.
I don't think people grasp that China is a major economic engine for the world. If COVID takes off there, it will affect everyone. The supply chain issues we have seen so far will look miniscule if they lose production capacity and logistics capabilities.
1-2
I posted a few examples of climbing COVID hospital admissions. This is happening in almost every state, which means that cases were climbing over a month ago. If you are a new follower, I have data for many countries and every state on my website. I update weekly.
My levels of H5N1 stress:
Avian outbreak - monitor
Spread to mammals - concern
Transmission to humans - anxiety
Human to human transmission - Oh s***
Sustained human to human transmission - Don't Look Up
@sojourner_blanc
COVID can cause many chronic diseases, data suggests that telomere damage ages the body by about 5 years, and it causes damage to the immune system.
HIV mostly just damages the immune system and is easily treated.
Finally, we don't know what else COVID might cause over time.
Excellent article. I have an extensive background in healthcare infection control. I will continue to fight for patient, staff, and visitor safety in these environments.
My question is if SARS-CoV-2 is every fully cleared from the body or if it lingers undetected like Hep B, Hep C, VZV, TB, HIV, etc until it re-emerges.
1-4
I started working on getting a template set up for adding XBB.1.16 to US states. I was working with my CA file as a starting point and something really jumped out at me related to healthcare associated (HAI) COVID.
Further evidence for my claim about how kids are taking a big hit with COVID right now. Don't listen to liars.
"In some parts of the country...the share of COVID-19 ER visits involving children ages 0 to 11 have already far surpassed older adults."
Antivaxxers: I won't get the vaccine because it has a microchip.
Elon Musk: I have approval for a new technology implant called Neuralink.
Antivaxxers: Sign me up.
Me:
I am willing to bet that Japan will be at it's 3rd highest hospitalization rate of growth in about a week. Why aren't we paying attention and preparing for our next surge?
1/2 If all of these diseases were airborne (some are), would people worry?
Botulism
Brucellosis
Tularemia
Legionella
Tuberculosis
Gonorrhea
Bacterial meningitis
Salmonella
Plague
Avian influenza
Rabies
HIV
VEE
Yellow fever
What do they have in common?
One of my coworkers just mentioned how she is having memory problems. She's had COVID twice, and has not heard of brain fog being associated with it. More messaging failures from the CDC.
4-4 We MUST get mandatory respiratory protection back in healthcare settings. This is a disservice to patients, staff, and visitors. Worse, the CDC making the move to make tracking HAI optional is almost criminal. I don't know how they can justify doing so when the data is clear.
A warning tale of two countries on what is coming soon. The first graph in each is of Omicron variants, but what is important is the gray area at the top right, which is where new variants are starting to get hold. The second is variants, hospitalizations, and ICU.
37-92% increases in chronic diseases after just a couple of years of COVID. This is going to look FAR worse when we are at 10 years out. Whatever is left of the healthcare system at that time won't be able to handle it.
The pandemic is not receding in the US. While it looks like cases are stable, hospital admissions are climbing. That's a good indicator that we are no longer capturing adequate test data due to home testing. With schools opening, this will likely get considerably worse.
Nipah is nasty. Nothing like having an outbreak of it among a population with immunosuppression from COVID. I would be concerned about this under normal circumstances. Now...๐ณ
Sweden, the darling of the right, libertarians, and let it run loose crowd, who are really just eugenicists, has hospitalizations climbing as well. When they tell me how well Sweden is doing, I compare them to three other similar populations.
I've tried to explain the importance of the preprint I tweeted yesterday. You can find it here. Hopefully I've translated some of the technical language into a COVID biology lesson that will be more understandable.
Quote from linked article.
"We have increasing evidence that, like measles, COVID-19 hobbles the immune system," University of Toronto's Colin Furness told CTV News Edmonton.
Preprint.
People may think that they had mild or asymptomatic COVID, but their blood vessels tell a much different story. The damage they sustained also spread to the tissues that they oxygenated.
I have removed the brain from someone who had a fungal infection of his frontal lobes. The lobes pretty much dissolved on touch. Mucormycosis is one other reason I still wear a respirator indoors.
๐๐ผ๐๐ถ๐ฑ-19-๐๐๐๐ผ๐ฐ๐ถ๐ฎ๐๐ฒ๐ฑ ๐ ๐๐ฐ๐ผ๐ฟ๐บ๐๐ฐ๐ผ๐๐ถ๐
Mucormycosis, also known as black fungus, is a rare but serious fungal infection caused by a group of molds called mucormycetes and can affect various parts of the body, including the sinuses...
COVID wastewater surveillance in on of the regions of Toronto. Someone explain to me how anyone claims the pandemic is over. Christmas is going to result in heartbreak for so many families.
I've had people tell me that COVID wastewater measurements are meaningless. Here are weekly hospitalizations and wastewater data in the Netherlands. I'd like to have them explain where there isn't a correlation.
Same study as my prior tweet.
"Our data conclusively demonstrate that SARS-CoV-2 is capable of infecting and replicating in macrophages within the coronary vasculature of patients with COVID-19."
Who can tell me what other virus hides in macrophages? Bueller? Bueller?
If you haven't had your bivalent COVID booster or influenza vaccine, get them both ASAP. If you don't have a good supply of respirators, get them ordered. Make sure you have adequate supplies of any prescriptions, and avoid crowds, especially indoors. It's looking to be rough.
This does not bode well. H5N1 has always been my biggest pandemic concern. Even if it doesn't become a direct problem for humans, if it is adapting to ruminants, it will cause a collapse in the food supply.
@ponymule
It wasn't showing up outside of avian populations much. We have much more in common with other mammals and since it is spreading in them, it's far more concerning now.
Those in denial are also generally politically conservative, and don't wear masks or get vaccinated. That isn't working out so well for them in the long run.
2/2 These are all either naturally airborne or can be through aerosolization. They are dangerous enough that are treated as BSL-3 agents under those conditions and should scare the crap out of people.
COVID is a BSL-3 agent.
Thank you for coming to my TED Talk.
I was a bit surprised to pick up >1000 followers in <24 hours this week. For those of you who don't know, I have a website with a lot of COVID data that I update each weekend. Inclusion is simply a matter of the availability of data beyond cases and deaths.
The last two years are looking more like they will be nothing in comparison to the infectious disease and chronic disease surges as a result of COVID infection. The future keeps getting darker and darker.
Wastewater concentrations and/or test positivity is climbing in almost every state. I think another surge is brewing. If you are a new follower, I update these each weekend, as well as the few countries with data and all of the metro areas.
Be sure to read the responses as well. I'm betting either a new COVID variant or, based on one report, severe Mycoplasma pneumoniae pneumonia driven by immune dysregulation from COVID. Watch for a global azithromycin shortage.
@dazult_pdempsey
Also remember all of the people who are buying into the antivaccine rhetoric around it being developed too quickly and thus refusing it. I bet they would feel the same about this.
An argument that most people wouldn't follow 5 days of isolation so get rid of the guideline is analogous to getting rid of speed limits because most people speed and telling people to slow down if they are in an accident.
I've never been a prepper until the start of the pandemic. With the arrival of supplies today, I can have 2 months of potable water stored in about 15 minutes and have about 4-5 months of emergency food.
1-6
Is anyone else feeling the futility of it all? I've easily spent thousands of hours trying to provide information and data and it feels like the only ones who listen are those who would have been protecting themselves anyway.
I might develop a COVID Wall of Shame of those who have been particularly damaging during the pandemic for future use. Who else needs to be included?
Douglas Frank
Emily Oster
Jay Bhattacharya
Leana Wen
Ryan Cole
Scott Atlas
Scott Jensen
Simone Gold (and all of AFD)
Vinay Prasad
ECMO is trending. For those who don't know, it's essentially temporary heart lung bypass, similar to what is used during open heart surgery. Tell me again how COVID is just a cold. Watch the colors on the map change from green to red and yellow soon.
"To put this into context, BF.7 is believed to have an R0, or basic reproduction number, of 10 to 18.6. This means an infected person will transmit the virus to an average of 10 to 18.6 other people. Research has shown omicron has an average R0 of 5.08."
@DMHerinya
Yes, pretty much the same things as COVID. A traditional vaccine was developed for it years ago. I am more worried about fomite transmission than I was with COVID. I don't have a good answer about foodborne.
It's almost like COVID sets one up for other infections.
"The average fatality rate so far this year has almost tripled compared with the five-year average."
US COVID hospital admissions by age. Why this is being called a "slight uptick" is beyond me, especially given that the number of hospitals reporting suspected COVID dropped by about 1/2 (dotted lines). Even though this data became available yesterday, it's two weeks old.
1-2 I really wonder if people ever truly clear COVID. 18 months of detection of it in macrophages is a bad sign in animal models.
"We detected replication-competent SARS-CoV-2 in bronchoalveolar fluid (BALF) Mac for up to 18โmonths after infection."
So, looking for more on the current Covid surge in Japan I stumbled upon a video (shortened for tweet).
This is so sad.
But, itโs our Govts we should be angry w/ for delivering us to a place where putting each other at risk of potentially life changing illnesses is common place.