Here comes "spatial-ATAC-seq"!!! A wonderful collaboration between my lab at
@YaleSEAS
and
@GoCasteloBranco
at
@karolinskainst
#epigenetics
#spatialomics
#spatialbiology
Spatial profiling of chromatin accessibility in mouse and human tissues | Nature
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for many friends following me on twitter, this sounds an old news :) . Indeed, the preprint was shared online back to June 2021. please check out
Spatial-ATAC-seq: spatially resolved chromatin accessibility profiling of tissues at genome scale and cellular level.
#spatialomics
#spatialbiology
Collaboration w/
@GoCasteloBranco
@Halene_lab
, Sai Ma, Joe Craft, and Mina Xu. Kudos to
@DengYanxiang
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again, kudos to my amazing postdoc
@DengYanxiang
, who will be joining
@penn
in a couple of months to start his own lab.
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@rkramann
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Thank you Rafael! Also, again, congrats on your recent Nature paper, which is a super important work for many of our heart disease patients, including my loved ones.
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also, thanks to
@marekbartosovic
and
@PKukanja
from
@GoCasteloBranco
for their enthusiasm and critical contribution to making this work much more impactful and revealing really new biological insights!
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Also, this manuscript has been improved so much with many collaborators
@Halene_lab
@MinaXu7
Joe Craft from
@yale
,
@marekbartosovic
@PKukanja
from
@GoCasteloBranco
lab at Karolinska,
@YangXiaoBME
,
@DrJohnMann
,
@DrMauraBoldrini
,
@theleonglab
and others from
@Columbia
.
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Also, huge appreciation to
@ItaiYanai
and other anonymous reviewers!!! your comments made this paper much better!!
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@RongFan8
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Great to see it published! Congrats to you and the entire team!
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@manimota
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Thank you Silas!! Appreciate the support from this fabulous community!
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@RongFan8
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Beautiful work! Congratulations, Rong and team!
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@KSusztak
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Thank you Katalin!! Also, thanks for the support of Yanxiang!
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put into a bigger context "spatial epigenomics" unlocked by this paper and another one "spatial-CUT&Tag" we published earlier in
@Science
. They are the foundational tools to put "spatial epigenomics" in the center stage of
#spatialomics
#spatialbiology
Spatial-CUT&Tag!
@ScienceMagazine
, unfolding a new chapter of
#spatialomics
🤗 . From my phenomenal postdoc
@DengYanxiang
of
@YaleSEAS
@YaleBME
,
@yalepathology
@YaleMed
@YaleCancer
Thanks to awesome collaborators
@GoCasteloBranco
@marekbartosovic
@PKukanja
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spatial-ATAC-seq shown in this
@nature
paper for the first time allows for spatially resolved unbiased genome-wide mapping of epigenetic cell state defined by accessible chromatin, potentially a new tool to identify cell types and build tissue atlases.
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@RongFan8
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Congratulations Rong and team! Fantastic work & opportunities!
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@MundAndreas
@YaleSEAS
@GoCasteloBranco
@karolinskainst
Thank you Andreas! Let's reconnect in the next few weeks and many more exciting opportunities to work on together!
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