Buckley Lab @LabBuckley Twitter profile

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Buckley Lab

@LabBuckley

7 months

I’m excited to announce that the Buckley Lab will be moving to Manchester University (division of Molecular and Cellular Function) in April 2024! We will soon be hiring at all levels (PDRA, RA, PhD, Masters) so please get in touch if you are interested.

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Buckley Lab

@LabBuckley

1 year

Very happy to see our paper on the cover of EMBO J today! Well done Xuan and the rest of the authors!

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Buckley Lab

@LabBuckley

2 years

Excited to share our new paper! We use polarising mESCs in Matrigel to show that, during epithelial polarisation of embryonic stem cells, the site of apical membrane initiation is defined by E-cadherin-mediated cell adhesion independently of cell division.

E‐cadherin mediates apical membrane initiation site localisation during de novo polarisation of...

image image Appropriate localisation of the apical membrane initiation site (AMIS) is critical for positioning a central and cohesive lumen during de novo polarisation of epithelial tubes and...

www.embopress.org

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Buckley Lab

@LabBuckley

2 years

Our review is out. Thank you Daniel for the exciting science discussions (and patience!) @StJohnstonLab @LabBuckley

Apical–basal polarity and the control of epithelial form and function

Nature Reviews Molecular Cell Biology - Apical–basal polarity is essential for epithelial cell form and function. Elucidating how distinct apical and basolateral compartments are established...

www.nature.com

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Buckley Lab

@LabBuckley

2 years

We really enjoyed the PLM conference last week - really exciting science and collaborative atmosphere. well done Millie for winning a poster prize! Looking forward to some lab brainstorming time now...

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Buckley Lab

@LabBuckley

6 months

Join us to study how cells build organs using optogenetics within zebrafish brains. 2 PhD projects available: BBSRC DTP deadline 19th January

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Buckley Lab

@LabBuckley

3 years

Here's our paper with the Clarke lab on how two separate polarised epithelia arise de novo in the middle of the developing zebrafish neural tube. Along the way we found an interesting connection between Crumbs, cell-cell separation and epithelial integrity

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Buckley Lab

@LabBuckley

1 year

I just found the 'what three words' address for my building. These are supposed to be random, right?!

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Buckley Lab

@LabBuckley

2 years

So excited to finally be able to contribute to this fantastic course again! Would highly recommend it for exciting science, collaborative colleagues and fun all round.

Marine Biological Laboratory (MBL)

@MBLScience

2 years

Zebrafish Development and Genetics Course Dates: July 28 - Aug. 11, 2022 Applications Due: April 26, 2022

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Buckley Lab

@LabBuckley

3 years

congratulations @millieerace for winning this year's @PDN_Cambridge symposium talk 1st prize!

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Buckley Lab

@LabBuckley

7 months

Just preserved 🌳 How great is this initiative - gave me a smile during my day

The Forest of Biologists

forest.biologists.com

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Buckley Lab

@LabBuckley

4 years

Zipping up the neural tube via @the_Node

Zipping up the neural tube - the Node

Matteo A. Molè & Andrew J. Copp Molè et al., Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. Dev.

thenode.biologists.com

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Buckley Lab

@LabBuckley

2 years

Our paper on AMIS localisation is out in the bioRxiv wild! Thanks to @MZG_Lab for their collaboration and helping us get the mESC model working

bxv_dev

@bxv_dev

2 years

CADHERIN mediated AMIS localisation

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Buckley Lab

@LabBuckley

2 years

We are currently looking for PhD students and postdoctoral fellows to join our research team! See links below:

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Buckley Lab

@LabBuckley

1 year

Helena's review on using optogenetics to dissect out shared mechanisms of apical-basal polarity and mitosis is out online - well done Helena!

Using Optogenetics to Investigate the Shared Mechanisms of Apical-Basal Polarity and Mitosis

Abstract. The initiation of apical-basal (AB) polarity and the process of mitotic cell division are both characterised by the generation of specialised plasma membrane and cortical domains. These are...

karger.com

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Buckley Lab

@LabBuckley

2 years

Thank you @Fernand49142950 and Gonzalo Herranz for the commentary on our paper!

Cadherin‐mediated adhesion takes control | The EMBO Journal

www.embopress.org

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Buckley Lab

@LabBuckley

3 years

awesome birthday present from the lab - thank you! Especially to the artist @millieerace !

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Buckley Lab

@LabBuckley

2 years

I'm so proud of my College, Pembroke, for running this 48 hour fundraising campaign to raise £70,000 to support a female Afghan Academic and offer them a safe place to continue their vital research. #AcademicAtRisk #PembrokeGives

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Buckley Lab

@LabBuckley

7 months

We strive to uncover how mechanics and biochemical signalling work together to shape epithelial organs during development. We use high resolution imaging and optogenetic approaches in vivo, within the zebrafish neural tube and in vitro, within multicellular mESC culture.

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Buckley Lab

@LabBuckley

7 months

The Cambridge lab will remain open until at least the end of 2024 so if you’d like to join us in Cambridge and move with us then even better!

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Buckley Lab

@LabBuckley

3 years

here is a lovely moment of mindfulness from Clare's sister. Enjoy

Alison Hitchens

@AlisonHitchens

3 years

Thanks #winterwatch for creating this with my footage 😍 starlings are my favourite bird and I think there must have been 50k starlings that evening on my local reserve they are just so extraordinary when they murmur

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Buckley Lab

@LabBuckley

4 years

Sad not to be going to Woods Hole again this year. But the MBL is putting on some virtual seminars for some of the courses. The zebrafish one is on July 7th. Fingers crossed we will be back next year!

Marine Biological Laboratory (MBL)

@MBLScience

4 years

Have you always wanted to take an MBL summer course? Or are you one of our alums? Since we can't bring students to Woods Hole this year, we're bringing the MBL to you with MBL Virtual Programming of our most popular classes!

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Buckley Lab

@LabBuckley

2 years

excellent opportunity for a lab manager in a super-cool lab

Weiner Lab

@OWeinerLab

2 years

The Weiner lab is looking to hire a full time lab manager. The position entails a good balance between research and helping run the lab. Ideal for undergraduates who are interested in getting some research experience for graduate school! Please share and RT.

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Buckley Lab

@LabBuckley

7 months

@AnjaliLamani Adverts will be out soon. Best to email directly if you are interested in discussing projects further, explaining what your research experience and interests are

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Buckley Lab

@LabBuckley

4 years

An atypical time for Cambridge visitors and residents.

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Buckley Lab

@LabBuckley

7 months

Looking forward to the 3rd Symposium tribute to Maxime Dahan in Paris 14th-15th December, focused on manipulation of cellular organisation by optogenetics and magnetogenetics.

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Buckley Lab

@LabBuckley

3 years

@rach_e_moore @ThompsonLab @PrinceLab_UofC @Beverley_CUBG @Munsterberg_Lab and you did a great talk! Those pesky axons ;)

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Buckley Lab

@LabBuckley

2 years

@rach_e_moore amazing - congratulations!!

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Buckley Lab

@LabBuckley

4 years

Cambridge streets have never been so empty at this season.

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Buckley Lab

@LabBuckley

1 year

Excited to be going to the PoL conference! I've arrived early - let me know if anyone else is around

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Buckley Lab

@LabBuckley

2 years

Well done Xuan and the rest of the team and thanks to @MZG_Lab for collaboration!

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Buckley Lab

@LabBuckley

2 years

@JamesWildman1 thanks James!

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Buckley Lab

@LabBuckley

2 years

@Marta_Shahbazi @ERC_Research huge congratulations Marta!! Very well deserved!

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Buckley Lab

@LabBuckley

2 years

We think that this provides a mechanism by which dynamic cells within a growing organ can establish and then maintain a coherent epithelial structure even while cells are moving and proliferating

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Buckley Lab

@LabBuckley

4 years

We just did this paper at journal club - really beautiful explanation of an unexpected role of Crumbs protein!

Kate Storey

@katestorey27

4 years

Our latest collaborative paper with Marysia Placzek's group on formation of the spinal cord central canal is out now #PLOSBiology : Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal

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Buckley Lab

@LabBuckley

4 years

I think I enjoyed hearing how this beautiful work was achieved even more than reading the original paper! @matteo_mole

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Buckley Lab

@LabBuckley

4 years

@Franze_Lab Thank you! One good thing about working from home is now we have more time for social media😁

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Buckley Lab

@LabBuckley

2 years

This is important, since it allows a continuous, fluid filled tube or cavity to arise in the centre of many different types of early organ, even when they are actively growing (and so the cells are moving around and dividing a lot).

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Buckley Lab

@LabBuckley

2 years

@A_Weberling thanks for your contributions!

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