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BMC

@BioMedCentral

7 years

Study finds that local-area proportions of green space is not a significant predictor of mental wellbeing

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7 years

Microparticles may be breast cancer's secret weapon to evade the immune system: #Cancer #BreastCancer

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3 years

Vitamin D deficiency is associated with compromised inflammatory responses and higher pulmonary involvement in COVID-19 affected patients, according to a study published in Respiratory Research.

Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients - Respir...

Background Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activat...

respiratory-research.biomedcentral.com

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1 year

A study in #BMCGastroEnterol finds that acute hemorrhagic colitis is characteristic in mild cases of the omicron variant of COVID-19 with gastrointestinal bleeding. The authors suggest keeping acute hemorrhagic colitis in mind when examining such patients.

A descriptive study of abdominal complications in patients with mild COVID-19 presenting to the...

Background COVID-19 is widely known to induce a variety of extrapulmonary manifestations. Gastrointestinal symptoms have been identified as the most common extra-pulmonary manifestations of COVID-19,...

bmcgastroenterol.biomedcentral.com

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5 years

On the theme of art, this paper and accompanying blog used mathematics to digitally explore paintings. Surprisingly they found that in Edvard Munch’s “The Scream”, the two sides of the bridge do not meet. #WorldHeritageDay

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6 years

Eye colour in wild species tends to be fixed, whereas humans and domesticated animals show multiple eye colours. Why is this?

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4 years

With #COVID19 dominating the news, it is easy to forget about other serious diseases, such as #dengue . Learn more about the spread of degue and the resulting implications.

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7 years

Up to 80 million bacteria are transferred during a 10 second kiss: #InternationalKissingDay

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2 years

A Review published in @GenomeBiology examines the recent development of statistical and machine learning methods in spatial transcriptomics, summarizes useful resources, and highlights the challenges and opportunities ahead.

Statistical and machine learning methods for spatially resolved transcriptomics data analysis -...

The recent advancement in spatial transcriptomics technology has enabled multiplexed profiling of cellular transcriptomes and spatial locations. As the capacity and efficiency of the experimental...

genomebiology.biomedcentral.com

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7 years

Popular #Microbiome research of 2017, #5 - Influence of diet on gut microbiome and implications for human health:

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@BioMedCentral

2 years

Awake prone positioning for 6 hours a day reduces the risk of endotracheal intubation and for 8 hours a day reduces the risk of hospital mortality in COVID-19 and acute respiratory failure patients, according to a study published in @Crit_Care .

Impact of exposure time in awake prone positioning on clinical outcomes of patients with COVID-19...

Background In patients with COVID-19-related acute respiratory failure (ARF), awake prone positioning (AW-PP) reduces the need for intubation in patients treated with high-flow nasal oxygen (HFNO)....

ccforum.biomedcentral.com

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8 years

It's #BrainAwarenessWeek , so put yours to the test with our #Neuroscience research quiz:

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5 years

A 10 second intimate kiss transfers 80 million oral bacteria 😘🦠 Happy #ValentinesDay

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10 years

SCIENCE FACT: The ruff bird has 3 types of male mates- one mimics a female just to seduce her: http://t.co/GylKsf7wL5 http://t.co/URLz0t7HKA

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5 years

Today is both the International Day of Women and Girls in Science AND #InventorsDay . So we thought it was the perfect opportunity to share a blog on five women that changed the world with their inventions: #WomenInScience

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5 years

The Wizard of Oz most influential film of all time according to research from the University of Turin @twitorino and published in the @SpringerOpen journal Applied Network Science:

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3 years

Vitamin D deficiency is associated with compromised inflammatory responses and higher pulmonary involvement in COVID-19 affected patients, according to a study published in Respiratory Research.

Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients - Respir...

Background Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activat...

respiratory-research.biomedcentral.com

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4 years

We’re committed to supporting the global response to the #coronarvirus by enabling access to the latest available research, evidence, and data on our dedicated page. All content is free and will continually be updated.

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3 years

An article published in @GenomeBiology introduces a new statistical framework, Clipper, that can identify interesting features with false discovery rate control from high-throughput data.

Clipper: p-value-free FDR control on high-throughput data from two conditions - Genome Biology

High-throughput biological data analysis commonly involves identifying features such as genes, genomic regions, and proteins, whose values differ between two conditions, from numerous features...

genomebiology.biomedcentral.com

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9 months

An article published in @Crit_Care provides a multidisciplinary and professional guideline for the rehabilitative therapy of patients with post-intensive care syndrome.

Guideline on multimodal rehabilitation for patients with post-intensive care syndrome - Critical...

Background Intensive Care Unit (ICU) survivors often experience several impairments in their physical, cognitive, and psychological health status, which are labeled as post-intensive care syndrome...

ccforum.biomedcentral.com

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2 years

In a @bugbittentweets blog post, @BiteOfAMosquito shares what he learned after reviewing "Preventing the Next Pandemic: Vaccine Diplomacy in a Time of Anti-Science," a new book by @PeterHotez .

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6 years

A review in @BMCBiology takes a look at the #evolution of the human #microbiome by comparing microbiomes from human populations, placing them in the context of microbes from humanity’s near and distant animal relatives. A review of the e:

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8 years

How to spot a statistical error, even if you are a non-statistical reviewer, full article: #PeerReview

How to spot a statistical problem: advice for a non-statistical reviewer - BMC Medicine

Statistical analyses presented in general medical journals are becoming increasingly sophisticated. BMC Medicine relies on subject reviewers to indicate when a statistical review is required. We...

bmcmedicine.biomedcentral.com

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2 years

Smokers who switched to either e-cigarettes or nicotine replacement therapy experienced a comparable positive cardiovascular impact after 3 months, according to a study published in #BMCMedicine .

Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking...

Background Smoking is a major risk factor for cardiovascular disease and smoking cessation reduces excess risk. E-cigarettes are popular for smoking cessation but there is little evidence on their...

bmcmedicine.biomedcentral.com

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5 years

In a recent @GenomeBiology editorial, @StevenSalzberg1 discusses how we can solve the growing problem of errors in genome annotation

Next-generation genome annotation: we still struggle to get it right

biomedcentral.com

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5 years

"When you play the game of thrones, you win or you die" New study in Injury Epidemiology examines characters' chances of survival in Game of Thrones

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5 years

While you're excitedly waiting for the Event Horizon Telescope black hole images, take a look at this virtual reality simulation by @jordydavelaar

Black holes in virtual reality

biomedcentral.com

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7 years

Hurry, there is less than 2 weeks to submit your entries to the 5th annual BMC Ecology Image Competition!

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6 years

Animals in the #ICU : how dogs (and cows) are helping critically ill patients

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1 year

A meta-analysis published in @Crit_Care suggests that propofol increases mortality by 10% in perioperative and critically ill patients. Large-scale studies are warranted to confirm the findings.

Propofol and survival: an updated meta-analysis of randomized clinical trials - Critical Care

Background Propofol is one of the most widely used hypnotic agents in the world. Nonetheless, propofol might have detrimental effects on clinically relevant outcomes, possibly due to inhibition of...

ccforum.biomedcentral.com

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6 years

#DNADay is celebrated globally on April 25th (the day that papers were published in Nature, on the structure of DNA). Try out our quiz on #DNA to see how you measure up: #DNADay18

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3 years

Ivermectin has no significant effect on preventing hospitalization of patients with COVID-19, according to a study published in #BMCInfectDis .

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized,...

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The scientific community has been investigating re-purposed treatments to prevent disease progression in...

bmcinfectdis.biomedcentral.com

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5 years

Parts of human DNA are of viral origin. Most are shared by all individuals, some are found in only a subset of people. New research shows another mechanism has introduced more inter-individual variation than previously appreciated. How can this be?

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7 years

It's #BiologyWeek - challenge yourself with our Big ‘Building Blocks of Biology’ Bamboozler

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2 years

Smokers who switched to either e-cigarettes or nicotine replacement therapy experienced a comparable positive cardiovascular impact after both a 3- and 6-month period, according to a study published in #BMCMedicine .

Medium- and longer-term cardiovascular effects of e-cigarettes in adults making a stop-smoking...

Background Smoking is a major risk factor for cardiovascular disease and smoking cessation reduces excess risk. E-cigarettes are popular for smoking cessation but there is little evidence on their...

bmcmedicine.biomedcentral.com

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7 years

Interested in science or photography? Enter our 'Research in Progress' photo competition!

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7 years

Popular on Twitter last month - article on the protective effect of helmet use in motorcycle and bicycle accidents:

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7 years

It’s #DNADay17 ! Test your knowledge of DNA with our quiz: & share your thoughts with us at #SN_DNADay

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6 years

Barbara McClintock is widely recognized as the founder of the field of transposable elements research. To honor her contribution, we selected her birthday (today) as #TransposonDay Find out how much you really know about the field’s founder in our quiz:

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3 years

Ivermectin has no significant effect on preventing hospitalization of patients with COVID-19, according to a study published in #BMCInfectDis .

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized,...

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) has changed our lives. The scientific community has been investigating re-purposed treatments to prevent disease progression in...

bmcinfectdis.biomedcentral.com

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2 years

Dexamethasone therapy is associated with an increased risk of pulmonary aspergillosis and mortality in severe and critically ill COVID-19 patients, reports research published in @Crit_Care .

Corticosteroids as risk factor for COVID-19-associated pulmonary aspergillosis in intensive care...

Purpose Corticosteroids, in particular dexamethasone, are one of the primary treatment options for critically ill COVID-19 patients. However, there are a growing number of cases that involve COVID-...

ccforum.biomedcentral.com

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3 years

What does SARS-CoV-2 sound like? A paper in @BMC_Bioinforma presents a tool for the sonification of the SARS-CoV-2 genomic RNA sequence.

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6 years

Higher nut intake is associated with reduced risk of cardiovascular disease, total #cancer and all-cause mortality, and mortality from respiratory disease, #diabetes , and infections #Diet

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5 years

Do you love writing about science? We're currently looking for a press officer to join the @SpringerNature external communications team to promote research across the Springer Nature portfolio, including BMC. You can find out more here: #scicomm

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4 years

20 years ago BMC launched as the first commercial open access publisher. Since then, it has pioneered a sustainable approach to OA and developed robust open policies for open research that have guided industry standards for OA. Happy Anniversary! #BMC20

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6 years

New study finds an association between increased time spent on #socialmedia in early adolescence and reduced well-being in later adolescence among girls.

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7 years

In an era of fake news, how do we ensure Cochrane Reviews remain trustworthy, efficient and sustainable?

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5 years

Congratulations to the winners of this year's #NobelPrize in Physiology or Medicine!

The Nobel Prize

@NobelPrize

5 years

BREAKING NEWS: The 2019 #NobelPrize in Physiology or Medicine has been awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability.”

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2 years

In the SDG Editorial Board Members blog collection, @GeraldGmboowa shares how his research on microbial genomics and computational approaches aligns with SDG3.

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9 years

Chicken #genomes have undergone the fewest changes since evolving from #dinosaurs http://t.co/5091LEXCC9 http://t.co/aiQEMn6rNx

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3 years

Awake prone positioning among patients with hypoxemic respiratory failure due to COVID-19 was safe, but it did not reduce the rate of endotracheal intubation compared with standard care, according to a study published in @Crit_Care .

Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19: the PROFLO...

Background The effect of awake prone positioning on intubation rates is not established. The aim of this trial was to investigate if a protocol for awake prone positioning reduces the rate of...

ccforum.biomedcentral.com

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3 years

A Review published in @Crit_Care discusses the use of sodium bicarbonate or renal replacement therapy in the ICU to normalize acid-base imbalance due to metabolic acidosis.

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1 year

A study published in @Crit_Care finds that early adjunctive methylene blue administration reduces vasopressor duration, cumulative fluid balance, and ICU and hospital length of stay among patients with septic shock.

Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial -...

Purpose Methylene blue (MB) has been tested as a rescue therapy for patients with refractory septic shock. However, there is a lack of evidence on MB as an adjuvant therapy, its’ optimal timing,...

ccforum.biomedcentral.com

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11 months

A Comment article published in @Crit_Care discusses how addition of a second-line non-adrenergic vasopressor may lead to improved outcomes mostly in less severe septic patients receiving lower doses of vasopressors.

Adjunctive vasopressors in distributive shock: How soon is early? - Critical Care

ccforum.biomedcentral.com

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1 year

A study published in @Crit_Care finds that early nutrition support in the ICU is significantly associated with increased mortality at day 28. This may challenge the current guidelines and practices, particularly concerning patients at low nutrition risk.

Association between early nutrition support and 28-day mortality in critically ill patients: the...

Background Current guidelines suggest the introduction of early nutrition support within the first 48 h of admission to the intensive care unit (ICU) for patients who cannot eat. In that context, we...

ccforum.biomedcentral.com

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8 years

Human #history , according to ancient DNA research. full article:

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7 years

Influence of #diet on the gut #microbiome and implications for human health:

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6 months

Aggressive intravenous hydration increases the mortality risk in severe acute pancreatitis (AP) and fluid-related complication risk in both severe and non-severe AP, according to a study published in @Crit_Care .

Comparison of clinical outcomes between aggressive and non-aggressive intravenous hydration for...

Background Current practice guidelines for optimal infusion rates during early intravenous hydration in patients with acute pancreatitis (AP) remain inconsistent. This systematic review and meta-an...

ccforum.biomedcentral.com

1

10

26

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@BioMedCentral

1 year

A meta-analysis published in @Crit_Care suggests that propofol increases mortality by 10% in perioperative and critically ill patients. Large-scale studies are warranted to confirm the findings.

Propofol and survival: an updated meta-analysis of randomized clinical trials - Critical Care

Background Propofol is one of the most widely used hypnotic agents in the world. Nonetheless, propofol might have detrimental effects on clinically relevant outcomes, possibly due to inhibition of...

ccforum.biomedcentral.com

1

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26

BMC

@BioMedCentral

6 years

We're very pleased to announce that Prof. Catherine Bowen and Prof. Keith Rome are the new Editors in Chief for the Journal of Foot and Ankle Research @jfootankleres @CathyJBowen

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5 years

@qikipedia Bonus trivia from the study: Burns accounted for 12% of deaths and legal executions 5%

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6 years

According to research there are 6 main emotional story arcs and @jk_rowling 's entire Harry Potter series can classified as a ‘Kill the monster’ plot #HappyBirthdayHarryPotter

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1 year

Apolipoprotein plays a critical role in modulating microglial responses and related lipid metabolism upon neuronal injury, which may cause neurodegenerative diseases, reports a study published in @MolNeuro

Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to...

Background Abnormal lipid accumulation has been recognized as a key element of immune dysregulation in microglia whose dysfunction contributes to neurodegenerative diseases. Microglia play essential...

molecularneurodegeneration.biomedcentral.com

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7 years

Feb 28 is #RareDiseaseDay & to mark this day, have a look at top #RareDisease research, blogs & a quiz here:

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8 years

'Knowledge should belong to everyone' - an interview with Barbara Burtness for #OAWeek2016 :

'Open access in action means that knowledge should belong to everyone'

In this interview, Barbara Burtness, Editor-in-Chief of Cancers of the Head and Neck, discusses the importance of removing barriers to accessing research and...

www.youtube.com

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7 years

#WorldAlzheimersDay 2017: earlier diagnosis is key to reduce impact of dementia - from @AlzDisInt 's Paola Barbarino

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6 years

Eye colour in wild species tends to be fixed, whereas humans and domesticated animals show multiple eye colours. A recent hypothesis published in Frontiers in Zoology explores why this might be.

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24

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@BioMedCentral

1 year

A study published in @Crit_Care finds that early adjunctive methylene blue administration reduces vasopressor duration, cumulative fluid balance, and ICU and hospital length of stay among patients with septic shock.

Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial -...

Purpose Methylene blue (MB) has been tested as a rescue therapy for patients with refractory septic shock. However, there is a lack of evidence on MB as an adjuvant therapy, its’ optimal timing,...

ccforum.biomedcentral.com

0

14

25

BMC

@BioMedCentral

1 year

Aggressive intravenous hydration increased the mortality risk in severe acute pancreatitis (AP) and fluid-related complication risk in both severe and non-severe AP, according to a study published in @Crit_Care .

Comparison of clinical outcomes between aggressive and non-aggressive intravenous hydration for...

Background Current practice guidelines for optimal infusion rates during early intravenous hydration in patients with acute pancreatitis (AP) remain inconsistent. This systematic review and meta-an...

ccforum.biomedcentral.com

0

15

24

BMC

@BioMedCentral

2 years

A Review published in Chinese Medicine describes how tea drinking, a herb-based complementary and alternative medicine therapy, can improve physical and mental health and promote the development of society through its chemical and cultural elements.

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@BioMedCentral

9 years

Distinct DNA methylation patterns could act as early diagnostic for #cancer of the #kidney http://t.co/TlX1d4likB http://t.co/1IevXB5FnJ

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7 years

Register free for this @SpringerNature #PeerRevWk17 event - 'Peer Review: What You Need to Know':

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7 years

Ancient DNA reveals the lion’s past and (perhaps) future #WorldLionDay

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@BioMedCentral

11 months

A study in @Crit_Care confirms that the current consensus threshold of 0.5 ml/kg/h over 6 hours to define oliguria may be too conservative. A cut-off of 0.2 ml/kg/h over 3 or 6 hours should be considered in definitions of oliguria.

Identification of an optimal threshold to define oliguria in critically ill patients: an observat...

Background The relevance of current consensus threshold to define oliguria has been challenged by small observational studies. We aimed to determine the optimal threshold to define oliguria in...

ccforum.biomedcentral.com

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@BioMedCentral

2 years

In critically ill patients, increasing protein intake after ICU admission is associated with a significantly lower in-hospital mortality and a shorter hospital discharge time, according to a study in @Crit_Care .

Protein intake and outcome of critically ill patients: analysis of a large international database...

Background Proteins are an essential part of medical nutrition therapy in critically ill patients. Guidelines almost universally recommend a high protein intake without robust evidence supporting its...

ccforum.biomedcentral.com

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1 year

BMC Ecology and Evolution is welcoming submissions to its new Collection "Paleoecology of Extinct Species,” which is guest edited by @PalaeoPittman and @wyc661217 .

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8 years

Test your knowledge of the latest #Neuroscience research for #BrainAwarenessWeek :

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@BioMedCentral

8 years

How does a stressful life affect DNA methylation during #aging ? A Q&A: #stress

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5 years

Today, we're very proud to present the winners of the BMC Ecology image competition 📸🦋🐒🦉🌋🕸

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1 year

IV vitamin C therapy in sepsis or septic shock patients significantly improved delta SOFA score and reduced the duration of vasopressor use, according to a meta-analysis of randomized controlled trials published in @Crit_Care .

The outcome of IV vitamin C therapy in patients with sepsis or septic shock: a meta-analysis of...

Background To update a meta-analysis of randomized controlled trials (RCTs) and further explore the outcome of IV vitamin C (IVVC) administration in sepsis or septic shock patients. Methods This...

ccforum.biomedcentral.com

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1 year

An article published in #BMCGenomics discusses OpenGenomeBrowser: the first self-hostable, database-independent comparative genome browser that drastically simplifies commonly used bioinformatics workflows and enables convenient and fast data exploration.

OpenGenomeBrowser: a versatile, dataset-independent and scalable web platform for genome data...

Background As the amount of genomic data continues to grow, there is an increasing need for systematic ways to organize, explore, compare, analyze and share this data. Despite this, there is a lack...

bmcgenomics.biomedcentral.com

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7 years

Statistical vs clinical significance: Are medical trials being misinterpreted? @BMCMedicine #Trials

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7 years

Schrödinger’s microbes - how do we know if microbes are dead or alive?

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5 months

A study published in @Crit_Care finds that timing from acute respiratory distress syndrome (ARDS) onset is an important factor in the effect of proning on oxygenation response in patients with ARDS.

Effects of early versus delayed application of prone position on ventilation–perfusion mismatch in...

Background Prone position has been shown to improve oxygenation and survival in patients with early acute respiratory distress syndrome (ARDS). These beneficial effects are partly mediated by...

ccforum.biomedcentral.com

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6 years

Cardio-Oncology is now the official journal of the International Cardio-Oncology Society @ICOSociety

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@BioMedCentral

6 years

Eye colour in wild species tends to be fixed, whereas humans and domesticated animals show multiple eye colours - why this might be?

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BMC

@BioMedCentral

10 months

A study in @Crit_Care confirms that the current consensus threshold of 0.5 ml/kg/h over six hours to define oliguria may be too conservative. A cut-off of 0.2 ml/kg/h over three or six hours should be considered in definitions of oliguria.

Identification of an optimal threshold to define oliguria in critically ill patients: an observat...

Background The relevance of current consensus threshold to define oliguria has been challenged by small observational studies. We aimed to determine the optimal threshold to define oliguria in...

ccforum.biomedcentral.com

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@BioMedCentral

6 years

Ancient DNA sequences shows that European leopards share a more recent ancestor with Asian leopards than with African leopards, which suggests that the European population was founded in the same out-of-Africa migration that founded the Asian leopards.

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7 years

Goth enough for #WorldGothDay ? What makes #bats special:

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1 year

In a BugBitten blog post, Krisztian Magori reflects on the benefits of attending workshops to keep up with novel research and develop connections with the professional community.

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8 years

Imbalances in gut bacteria can lead to insulin resistance and type 2 #diabetes : #microbiome

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5 years

New research compares cancer risks between alcohol and tobacco to help people make better informed judgments

How many cigarettes are there in a bottle of wine?

biomedcentral.com

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@BioMedCentral

1 year

A Review published in @GenomeBiology examines the recent development of statistical and machine learning methods in spatial transcriptomics, summarizes useful resources, and highlights the challenges and opportunities ahead.

Statistical and machine learning methods for spatially resolved transcriptomics data analysis -...

The recent advancement in spatial transcriptomics technology has enabled multiplexed profiling of cellular transcriptomes and spatial locations. As the capacity and efficiency of the experimental...

genomebiology.biomedcentral.com

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@BioMedCentral

7 years

A very happy 91st birthday to Sir David Attenborough!

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5 years

Human African Trypanosomiasis, also known as sleeping sickness, is a fatal neglected tropical disease of which approximately 70 million people living in sub-Saharan Africa are at risk.

Rare Fatal African Sleeping Sickness May Have Easy And Accessible Cure - On Medicine

The World Health Organization's goal of eliminating the fatal neglected tropical disease Human African Trypanosomiasis (HAT), also known as sleeping sickness, may be realized by as early as 2020...

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How to spot a statistical error, even if you are a non-statistical reviewer, full article: #PeerReview

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Food for thought this #ValentinesDay : there is an average transfer of 80 million bacteria per 10 seconds of #kissing .

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A study published in @Crit_Care shows that early, home-based rehabilitation interventions for patients with Post-Intensive Care Syndrome-related symptoms are feasible and are perceived positively by patients and professionals.

Feasibility of a home-based interdisciplinary rehabilitation program for patients with Post-Inten...

Background Survivors of critical illness experience long-term functional challenges, which are complex, heterogeneous, and multifactorial in nature. Although the importance of rehabilitation interv...

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How temperature influences the fitness of fish and their tapeworm parasites

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A Review published in @Crit_Care provides 10 expert tips on enteral nutrition for daily practice in intensive care units.

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