Director, Cntr for Translational Social Neurosci, Conte Center for Oxytocin & Social Cognition @ Emory & Cntr for Social Neural Networks, Tsukuba Univ Japan.
Check out
@RFroemke
's and my new review on Oxytocin, Neural Plasticity, and Social Behavior. Nice overview of OXT modulation of social neural circuits and "modulation of modulation" Fun integrating our two perspectives.
CRISPR Oxtr-Cre voles created by
@KengoHorie
& in collab w/ K. Nishimori!! Kengo labeled Oxtr cells projecting to NAc as a proof of principle. Intersectional Oxtr circuit manips (opto-, chemogenetics) & behavior in voles will follow.
Excited to share our detailed RNAscope mapping of oxytocin receptor in vole brain, relation to DA receptors, SNPs & mRNA-protein mismatch. Evidence of presynaptic function! Great teamwork by Kiyoshi Inoue,
@Charles53738010
&
@KengoHorie
!
Wonderful to share a meal with some of the best social neuroscientists in the world at the Keystone Symposium here in Korea!
@erichjarvis
@kaymtye
@Froemkelab
, David Anderson, Lisa Stowers, Hee-Sup Shin, Rob Malenka, Rui Oliveira. Fantastic talks by all!
“Love is one of our most powerful emotions, inspiring some of the greatest art, literature and conquests of human history....” Our new review discusses the neurobiology of pair bonding at a circuit level. Check it out at . Proud of this one!
I am looking forward to the return of real life conferences in 2022. I’m particularly excited about this awesome Neurocircuitry of Social Behavior meeting in Korea next Fall. A Dream Team of speakers! Mark your calendar!
It’s gratifying getting recognition @ home from your own institution! I’m particularly excited to receive this year’s recognition from
@EmoryMedicine
School of Medicine after ~29yrs
@EmoryUniversity
. Not possible without trainee contributions!
Mom will finally hear my talk!
Congratulations to William P. Timmie Professor of Psychiatry and Behavioral Sciences
@lyoun03
for receiving the presitigious
@EmoryMedicine
2023 Dean's Distinguished Faculty Lecture and Award! Dr. Young will give his honorary lecture on May 25.
Pierre Ferrari and I are organizing an oxytocin/vasopressin & social behavior meeting May 27-30 2022! A follow-up of the 2018 meeting which was fantastic!! An amazing experience! Hope to see you there!! Great chance to visit Sicily and Palermo!
Making Xmas treats with my mom. She knows I work l with rodents “at the college” so she made monogamous prairie voles and transgenic mice for holiday snacking.
Our son tested positive for coronavirus yesterday. Asymptomatic & lives with us, college closed.
@AnneZMurphy
& I have been so careful when going out for necessities. It’s scary knowing that home is the most dangerous to be now.
“How little we know, how much to discover, what chemical forces flow from lover to lover”
—Frank Sinatra
Congratulations
@sarah_blumen
on her new review in 🧠❤️
The Neurobiology of Love and Pair Bonding from Human and Animal Perspectives
Oxytocin signals through synapses (~ethernet) or as a hormone (~broadcast satellite). But local diffusion from axonal release (~WiFi) may be most important in CNS for behavior. We show WiFi OT signaling in spinal cord regulates male sex behavior!
Love our new lab logo created by
@mbenskydesigns
! I highly recommend him if you need a cool lab/center logo.
p.s. Lab named for the spirit of the lab team!
We’ve just concluded the first
@KeystoneSymp
on the Neurocircuitry of Social Behavior in 🇰🇷! Thanks to all the fantastic speakers and attendees, it was a great success and memorable meeting! Fully 😷 until 📸.
Recruiting a postdoc or grad student to explore genetic mechanisms regulating variation in brain oxytocin receptor & social behavior w CHIP-Seq & ATAC-seq in prairie voles. Email me if interested. See
pls RT
@emorygmb
"It is now clear that oxytocin and vasopressin in the brain are released extrasynaptically from dendrites and from varicosities in distant axons."
👍
The multiple faces of the oxytocin and vasopressin systems in the brain
Was great to run in Central Park this AM after my 1st trip to NYC in a while. Had a blast giving a talk & visiting
@ScottRusso_CAN
& the wonderful faculty at
@MountSinaiPsych
& Neurosci
@IcahnMountSinai
!! Reminded me how important in person talks are!
Had a great time talking brain science to potential next gen scientists 🧠👩🏾🔬🧑🏼🔬👨🏿🔬👩🏽🔬at a K-5 after school program in ATL yesterday with my 3 daughters!! A family affair! Just as I did for them when they were that age!
#scienceiscool
!
How do we reconcile this with 40 yrs of OT-BBB dogma? Things are never as simple as we first believe. Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice | Communications Biology
Congrats to
@DrZoePhD
for being elected associate member of
@ACNP
and for winning 1st place in the poster award Monday night and speaking at a panel on the importance non-traditional model organisms
#ACNP2018
. So proud of her! You Rock Zoe!
Such a fantastic group of participants at the 2022 Erice Oxytocin/Vasopressin Workshop in Sicily. Wonderful discussions & presentations on OXT/AVP & social behavior by trainees & established investigators! Bonding continues tomorrow in our excursion to Greek ruins!
Much more to come with genetically modified prairie voles from us and others. This was a teaser. CRISPR is revolutionary for comparative behavioral neuroscience.
Oxytocin receptor knockout prairie voles generated by CRISPR/Cas9 editing show reduced preference for social novelty and exaggerated repetitive behaviors The first study to report targeted specific gene modification in prairie voles, from
@lyoun03
+ team
We are recruiting for a NHP 🐒🧠 behavioral neuroscience faculty position at Emory Primate Center and Dept of Psychiatry in Atlanta! Great environment, colleagues and resources. For more info see 👇👇 Come join us!!
So proud of my daughter Olivia (k
#2
) for graduating from Vanderbilt
@vupeabody
w/ Master’s in Human Development Counseling! Gonna make a difference in kids lives! 👩🎓👦🧒👩🏫.
Oxytocin induces long-lasting adaptations within amygdala circuitry in autism: a treatment-mechanism study with randomized placebo-controlled design. - PubMed - NCBI
Congrats to
@KengoHorie
who after spending the last few yrs in the lab creating transgenic voles, incl new Oxtr-Cre voles, is leaving for a Asst Prof position
@okayama_uni
! Be on the look out for his papers from the lab! Thanks for helping transform the lab Kengo!
Congratulations Dr. Charles Ford
@Charles53738010
for a successful PhD defense today! Clear & thought provoking presentation! Relating brain areas to Game of Throne characters was brilliant for non-neuro folks! Navigated tough ??s like “do voles have theory of mind?” 🧑🎓
Important paper!
Plasma oxytocin can be reliably measured without extraction
Extracted and unextracted samples are highly correlated
Results are dependent on the immunoassay
Some commercial assay kits are susceptible to matrix interference.
Recruiting a postdoc or grad student to explore genetic mechanisms regulating variation in brain gene expression regulating social behavior w CHIP-Seq and ATAC-seq in prairie voles. Email me. See …]
@JennyMerritt1
@emorygmb
pls RT
Satisfying to see
@FoxNews
transforming & being positive about Biden & Harris. Squashing reports of fraud. Remarking how inspirational Harris is for many. Saying what went wrong w Trump. Reporting the celebrations! Many folks where I’m from only get news from
@Foxnews
.
15 years ago tomorrow
@AnneZMurphy
and I tied the knot on a beach in Costa Rica 2 years after meeting at
@IBNS
in Capri
#IBNS2012
. Happy Anniversary honey!! What a beautiful family! All grown up now! Time flies!
Happy to see this collab w Hirotaka Sakamoto & Takumi Oti out in
@CurrentBiology
. Oxytocin promotes male sexual activity via NON-SYNAPTIC release in spinal cord. Similar mechanisms likely occur in brain to affect behavior: Like WiFi in the CNS! 🎉
Happy to share a new commentary w
@Charles53738010
: Refining oxytocin therapy for autism: context is key! OXT must be paired w behavioral therapy, next generation drugs needed! Response to recent negative OXT clinical trial in NEJM.
Oxytocin receptor knockout prairie voles generated by CRISPR/Cas9 editing show reduced preference for social novelty and exaggerated repetitive behaviors Horm&Beh
Sunrise from my balcony at the Erice Sicily Oxytocin/Vasopressin conference this morning! Great talks so far this AM from
@veenemalab
@stevewcchang
& V Grinevich.
“reciprocal connectivity between OT neurons and extrahypothalamic OTR neurons to tune OT neuron activity depending on the behavioral context”
Oxytocinergic Feedback Circuitries: An Anatomical Basis for Neuromodulation of Social Behaviors
Social experience changes how oxytocin modulates the nucleus accumbens by recruiting endocannabinoids! Cool new study by
@AmelieBorie
&
@LiuLabEmory
and team! Check it out!!!
Super excited to welcome Zack Johnson
@bluedotguy
as a new TT Assistant Professor of Psychiatry
@EmoryBrain
& in my Division at Emory Primate Center
@ENPRCnews
! Be on the lookout for some amazing 🧬🧠🔬 coming from his lab!
@neurophd_emory
Was a pleasure to chat w/
@KarlDeisseroth
about his fabulous new book, Projections. I highly recommend it for holiday reading! Inspiring for neuroscientists/psychiatrists of all career levels.
Projections: a conversation with Karl Deisseroth via
@YouTube
Incredibly cool innovation!!
@iaahmed123
is making important new tools for the oxytocin research community working in brain or periphery! A rising star!!
#sbn2022
Interested in this 👇 Sicily OT/AVP meeting? Who would you ♥️ to see speak? We want to build a program inclusive of the most exciting OT/AVP social 🧠 from diverse perspectives & model organisms 🐒🦍🦜🐀🐕🐠. DM me. Self nominate!
Pierre Ferrari and I are organizing an oxytocin/vasopressin & social behavior meeting May 27-30 2022! A follow-up of the 2018 meeting which was fantastic!! An amazing experience! Hope to see you there!! Great chance to visit Sicily and Palermo!
Wonderful concluding day of the 2022 Erice Sicily Oxytocin/Vasopressin Workshop. A resounding success I’d say. Pier Francesco Ferrari (Co-organizer) joined us on the last day after testing negative (4x)! Join in in 3-4 yrs for the next one!!
Join us in Atlanta for the 2024 World Congress of Neurohypophyseal Hormones (WCNH) for a premier oxytocin & vasopressin meeting May 16-19! Pls RT!
The website will post details on the program and registration as they are available.
Congratulations Dr. Desiree DeLeon
@dcossyle
for successfully defending your PhD dissertation!! Great job! It’s been a pleasure having you in the lab the last few years!! Good luck in the next stage of your career!!
Mark your calendar for this 2020 Keystone Symposia on the Neurocircuitry of Social Behavior in Daejeon South Korea! Program includes
@kaymtye
@DulacLab
& many more! Organized by Hee-Sup Shin, Hailan Hu,
@carmensandi10
and
@lyoun03
Oxytocin increases eye contact in bonobos but eye avoidance in chimpanzees! Wonder if there are species differences in 🧠OXT/AVP fibers or receptors in 🧔🐵apes!
@cn_rogers
Divergent effects of oxytocin on eye contact in bonobos and chimpanzees
Super excited to co-mentor
@jarildy
along with
@muruganmalu
! Together, we are going to do some super cool science on the 🧠 circuitry of social reward, salience and bonding in mice and voles using state-of-the-art tools and animals! Keep an eye out!
HAVE YOU HEARD??? ITS
#BlackInNeuroWeek
!!
My name is Jarildy L. Javier and I'm a Neuro PhD student at Emory. I'm interested in ecology, evolution & neuroscience and my thesis will focus on social behavior. I am SO excited for
#BINW21
and y'all should be too!
#BlackinNeuroRollCall
Harnessing the healing power of ❤️!
@Charles53738010
& I propose a novel strategy to tap into the healing power of social relationships by studying the social 🧠! Comment on 🤯work by
@hkiaris1
on love & cancer using Peromyscus! Impossible w 🐁! RT
Just got a new Departmental head shot. Like school pictures, but only offered to faculty who hadn't had one in the past 10 yrs! Interesting to compare with previous pics! 📅 2007, 2010, 2013, 2021 📅. Time flies!!!
It was wonderful to enjoy lab picnic together, 1st in over a year. We talked a little science, played some cornhole and had a whole lotta fun! A great international 🌏🌍group!
Just concluded 3 conferences in Uganda & Kenya on the 🧠🔬🧬of love, bonding & nurturing children to bring new perspectives on relationships, health & female genital mutilation for community leaders, teachers, councilors, clergy & spouses. Next up-Tanzania.
#oxytocin
#EndFGM
Check out the amazing
@KeystoneSymp
: Neurocircuitry of Social Behavior in S. Korea Sept 4-7, 2022. Dream Team of speakers! Great science, exotic location & 🌶️🦑🍲
Scholarship/Abstract deadline June 7📅
Program & dates:
Pls RT
Super proud of Sarah Blumenthal
@sarah_blumen
for receiving the
@neurophd_emory
Service Award for her many outstanding contributions to the Emory Neuroscience Program! So well deserved! 👏🥇🎉🥳
Also be on the lookout for her outstanding paper coming soon! 🤞
Seems appropriate today to give a shout out to
@BoenderAJ
for this excellent paper in
@SBNTweets
on the promise of CRISPR for behavioral neuroscience in non-traditional models
Oxytocin, vasopressin and social behavior in the age of genome editing...
“This is a very important study because it does say that just willy-nilly giving daily administrations of oxytocin is not going to lead to improvement,” Its not a vitamin!
Oxytocin, the 'sociability' hormone, didn't help kids with autism, study finds
Oxytocin has opposite & sex-specific effects on mate preference in Medaka🐟! Proud of this
@PNASNews
paper w
@latipes
& Saori Yokoi! . Pics 👇show us collecting wild Medaka 🐟in Japan! Returning to Center for Social Neural Networks, Tsukuba next week!
Happy Valentines Day! “Love is one of our most powerful emotions, inspiring some of the greatest art, literature and conquests of human history”. “Oxytocin is the grease of the Social Brain!” Read more at .
I highly recommend S4SN2024! Human and animal social neuroscience together in each symposium. A great chance to experience Japan during cherry blossom 🌸 season & great 🍣! A short 45 min 🚄🚆ride to Tokyo! Excited to co-host w/
@SonokoOgawa
!
Had a great workshop on oxytocin & the biological basis of love & bonding with psychiatrists, psychologists, students from Bethany Hospital, Kampala Uganda today! 5 more in Uganda, 2 in Kenya! Great discussion, I learned a lot! Now if only my lost luggage will arrive from US!
@hopihoekstra
@HarvardOEB
@MCZHarvard
E.O. Wilson was Truly a giant in social biology! As a 2nd year grad student in 1991 I was THRILLED to get an actual letter addressed to me from E.O. Wilson- autographed. It was a desk rejection from PNAS for my first paper submitted. I have the letter to this day.
Excellent talk by
@BoenderAJ
at the Erice OXT/AVP workshop showing his AAV-CRISPR vector to disrupt OXTR in any rodent species! He is happy to share the tools.
Happy to see this collaboration w/
@lamcgraw
@joeltripp
@evolbrain
& others out! Several yrs in the making. Great job
@joeltripp
in pulling it together!
Comparative transcriptomics of mating/bonding in prairie & meadow voles:
It’s 2 weeks post 2nd Pfizer 💉 and time for COVID hair to go.
@AnneZMurphy
complained so much about my COVID growth! 1st time w/o beard in over a decade!
Cool paper by
@Jen_L_Cornish
showing effects of peripheral OXT are mediated by vagus nerve! Could this be true for social effects too? The Vagus Nerve Mediates the Suppressing Effects of Peripherally Administered Oxytocin on Methamphetamine Self-Admi…
Abstract & Scholarship submission & early registration deadline coming up soon, June 7! A Dream Team of speakers! Great opportunity to network with current & future leaders in the field in an exciting location!
Pls RT!
Was recently in Japan renewing my long term friendship with Katsuhiko Nishimori. We have had great “bromance” times together over the years and excellent science collaboration!! These pics are 17 yrs apart.... many more memories to come... be safe.
Super proud to see my daughter’s
@leighannayoung
first 1st author paper on hormone mod of 🐒🐒 social behavior! Important work for successful management of 🐒 breeding colonies used in health research!
@NPRCnews
@yerkesnews
Excited to see our 1st Conte Cntr ASD-OT paper led by
@eandari24
published. Reports relationships btw OXTR methylation, ASD diagnosis & symptom severity & rsFC btw areas involved in social cognition & reward. . Stay tuned…several more to come!
Congrats to
@AmelieBorie
&
@LiuLabEmory
! Sex-specific & social experience-dependent oxytocin–endocannabinoid interactions in nucleus accumbens: implications for social behaviour | Philosophical Transactions of the Royal Society B: Biological Sciences